Comfortis® (Spinosad) for dogs and cats

A fast, safe and effective flea treatment for the infestations on dogs and cats. Comfortis kills fleas before they lay eggs and keeps killing fleas for a full month with each dose.

Why Choose Comfortis® for Your Pet?

  • Beef Flavored Chew

    Convenient flavored tablet avoids mess. No need to isolate your pet from children or other animals after treatment.

  • Acts Fast

    Shown to kill 100% of fleas on dogs and 98% of fleas on cats in just four hours in controlled laboratory studies.

  • Focused Treatment

    The right choice when all you need is flea control.

Ready to protect your dog or cat from fleas?

Comfortis, Elanco and the diagonal bar logo are trademarks of Elanco or its affiliates.

Comfortis for dogs indications:

COMFORTIS kills fleas and is indicated for the prevention and treatment of flea infestations (Ctenocephalides felis) for one month, on dogs and puppies 14 weeks of age and older and 5.0 pounds of body weight or greater.


Comfortis for dogs Important Safety Information (ISI)

Serious adverse reactions have been reported following concomitant extra-label use of ivermectin with Comfortis. Use with caution in breeding females and dogs with pre-existing epilepsy. The safe use of Comfortis in breeding males has not been evaluated. The most common adverse reactions reported were vomiting, depression/lethargy, anorexia, ataxia, diarrhea, pruritus, trembling, hypersalivation and seizures. Post approval experience continues to support the safety of Comfortis when used concurrently with heartworm preventives according to label directions. For complete directions for use and safety information read the product label or ask your veterinarian.


Comfortis for cats indications:

COMFORTIS kills fleas and is indicated for the prevention and treatment of flea infestations (Ctenocephalides felis), for one month, on cats and kittens 14 weeks of age and older and 4.1 pounds of body weight or greater.


Comfortis for cats Important Safety Information (ISI)

For cats: Use with caution with concomitant extra-label use of ivermectin. The safe use of Comfortis in breeding, pregnant, or lactating cats has not been evaluated. The most common adverse reactions reported were vomiting, lethargy, anorexia, weight loss, and diarrhea. For complete directions for use and safety information read the product label or ask your veterinarian.