Zenrelia controls itching and inflammation associated with skin allergies in dogs at least 12 months of age. It is an oral tablet, dosed once daily in accordance with your dog’s weight.

Zenrelia begins to work quickly after dosing.¹

¹Forster S, Boegel A, Despa S, et al. Comparative efficacy and safety of ilunocitinib and oclacitinib for the control of pruritus and associated skin lesions in dogs with atopic dermatitis. Veterinary Dermatology. 2025; 1-10.

Zenrelia is approved to treat skin allergies in dogs, including canine atopic dermatitis (CAD), flea allergy, food allergies, and contact dermatitis.

Zenrelia should be given once daily. Use can be started or stopped at any time, without loading doses (multiple doses a day) or tapering (slowing stopping over time). Discuss any dosing changes with your veterinarian.

Zenrelia is labeled for use in dogs as small as 6.6 lbs.

Zenrelia does not contain pork, beef, soy, lactose or dairy.²

²Elanco Animal Health. Data on File.

Zenrelia tablets are not flavored.²

²Elanco Animal Health. Data on File.

Zenrelia can be administered with or without food.

Yes.  One intended use for Zenrelia is canine atopic dermatitis (CAD) which is a chronic condition, so there is no limit on duration of use.

Zenrelia has a Boxed Warning advising to pause use for at least 28 days to 3 months before and for at least 28 days after your dog receives a vaccine. Your veterinarian will determine how long a pause is right for your dog. As with any prescription, follow your veterinarian’s instructions for giving your dog Zenrelia.

No, Zenrelia is for use in dogs only.

If your dog misses a dose, you can simply restart treatment when you remember, taking care to not to administer more than the daily dose prescribed by your veterinarian. Always consult your veterinarian if you have medication questions for your pet.

If at least a partial dose was swallowed, then it is likely that your vet may have you monitor your pet for increased itchiness but recommend waiting till the following day to continue the medication as prescribed. Always consult with your veterinarian regarding medication questions for your pet.

The Boxed Warning provides important information about appropriate use of Zenrelia, which your veterinarian has taken into account when prescribing the medication for your individual dog. Specifically, the Boxed Warning advises discontinuation of Zenrelia for at least 28 days to 3 months prior to vaccination and withholding Zenrelia for at least 28 days after vaccination due to the risk of inadequate immune response to vaccines. Zenrelia is FDA-approved, meaning it has undergone rigorous testing and has been shown to be safe and effective when used according to these label instructions.