K9 Advantix® II for Dogs

Don't let your dog fear the great outdoors. K9 Advantix® II kills and repels fleas, ticks and mosquitoes too. It works through contact, so they don't have to bite your dog to die.

A lab puppy standing up with K9 Advantix ® II for dogs package overlay

Why choose K9 Advantix® II for your dog or puppy?

  • An icon of a flea, tick, and mosquito
    Kills and repels

    Starts to kill through contact within 12 hours — so pests don’t have to bite your dog for it to work.

  • An icon of a vet cross with a paw print in the center

    No prescription needed. Effective on dogs and puppies 7 weeks of age and older that weigh 4 lbs. or greater.

  • An icon of an applicator

    Goes on in seconds. Apply drops directly on your dog's skin — no hard-to-swallow pills.

  • An icon of a water drop within a shield
    30 days of waterproof protection

    Apply K9 Advantix® II monthly. It becomes waterproof after 24 hours.

A lab puppy walking with an icon of a flea, tick, and mosquito repellant for dogs

K9 Advantix® II provides mosquito protection, too.

Unlike most competitors, K9 Advantix® II not only helps repel fleas and ticks for four weeks; it also kills and repels mosquitoes that may transmit heartworm disease and West Nile virus. 

Compare K9 Advantix® II to Frontline® Plus as well as other brands.


Based on label claims. 

Do not use K9 Advantix® II on cats.


Find the right K9 Advantix® II option for your dog.

K9 Advantix® II comes in different dosage sizes and package quantities. For your convenience, you can purchase them in packs of 2, 4 or 6. 

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K9 Advantix® II fights the misery of biting fleas, ticks and mosquitoes. Get it for your dog or puppy today.

How to apply K9 Advantix® II on dogs.

It's easy to apply K9 Advantix® II flea, tick and mosquito treatment on your dog. Simply watch this video, follow the steps below or refer to your product package instructions. Be sure to apply it while indoors.

K9 Advantix® II directions for application


Hold applicator tube in an upright position. Pull cap off tube.


Turn the cap over and push the other end of the cap onto the tip of the tube. Twist the cap to break the seal, and then remove the cap from the tube.


Evenly apply the entire contents of the tube along the top of the dog’s back, from the shoulder down to the base of the tail. The number of spots depends on the size and weight of your dog (please refer to the product label).


At each spot, part the hair until the skin is visible. Place the tip of the tube on the skin and gently squeeze a portion of the solution on the skin.

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K9 Advantix, Elanco and the diagonal bar logo are trademarks of Elanco or its affiliates. 

Do not use K9 Advantix® II on cats.

Frontline and NexGard are registered trademarks of Boehringer Ingelheim Animal Health. Bravecto is a registered trademark of Intervet, Inc. dba Merck Animal Health. PetArmor is a registered trademark of Velcera, Inc.