Advantage® II flea treatment for cats and dogs

Fight the misery of biting fleas with Advantage® II, a leading brand in flea prevention for over 25 years. This easy-to-apply topical flea treatment starts killing fleas within 12 hours and lasts for 30 days, no prescription required.

How does Advantage® II work?

  • Green drawings of a flea through different life cycles
    Breaks the flea life cycle

    Advantage® II’s ingredients kill all flea life stages — fleas, flea eggs and flea larvae — to prevent re-infestation.

  • An Advantage II topical applicator icon
    How to apply Advantage® II

    Apply Advantage® II directly to your pet’s skin.* It goes on in seconds — no hard-to-swallow pills.

  • A green target icon
    Kills through contact

    Unlike oral flea treatments, Advantage® II kills fleas through contact so they don’t have to bite your pet to die.

  • Number 30 outlined by a clockwise arrow
    30-day continuous protection

    How long does Advantage® II take to work? It starts killing fleas within 12 hours and and keeps working all month long.

*See product label for complete directions for use.

Ready to protect your pet with vet-recommended
Advantage® II?

Advantage® II spot-on flea treatment for cats, dogs and ferrets, too

Close-up of a cat and the Advantage II Large Cat pack

Advantage® II for Cats

  • For cats and kittens at least 8 weeks old 
  • Cat sizes: Kitten (2-5 lbs.), small cat (5-9 lbs.) and large cat (over 9 lbs.)
  • Package quantities: 2, 4 and 6 doses 
  • Product label
Close-up of a dog lying on a mat and the Advantage II Small Dog pack

Advantage® II for Dogs

  • For dogs and puppies at least 7 weeks old 
  • Dog sizes: Puppies and small dogs (3–10 lbs.), medium dogs (11–20 lbs.), large dogs (21–55 lbs.) and extra-large dogs (over 55 lbs.) 
  • Package quantities: 4 and 6 doses 
  • Product label
Close-up of a ferret being held in human hands and the Advantage II Ferret pack

Advantage® II for Ferrets

  • For ferrets at least 10 weeks old 
  • Ferret sizes: 1+ lbs.
  • Package quantities: 2 doses
  • Product label

Find Advantage® II for Ferrets at your favorite pet care retailer.

Arm yourself against parasites with the Advantage® Family

The Advantage® Family is dead serious about pet parasites. That’s why we offer a full line of products designed to take out fleas, ticks, mosquitoes and more on your pet and around your home. If you're ready to show these bloodsuckers who’s boss, it's time to join the Family.

Top questions about Advantage® II for cats and dogs

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June 2024

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