Advantage®&nbsp;II is a comprehensive treatment that works quickly and starts killing fleas on your cat or dog within 12 hours. It's waterproof after 24 hours and lasts 30 days. This convenient monthly topical solution kills fleas through contact so they don’t have to bite your pet to die.

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Advantage® II flea treatment for cats and dogs

<h2>Why choose Advantage®&nbsp;II flea control?</h2>

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Kills fleas, flea eggs and flea larvae to prevent re-infestations.

Kills and prevents

Easier than a flea collar. Goes on in seconds. Apply directly to pet’s skin — no hard-to-swallow pills.

Easy-to-apply


Apply Advantage®&nbsp;II monthly. Starts killing fleas on your cat or dog in 12 hours, waterproof after 24 hours.

30-day continuous protection

Available over the counter whenever you need it.

No prescription needed

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<h2>Advantage®&nbsp;II is fast and effective</h2>
Advantage®&nbsp;II flea treatment for cats and dogs goes on in seconds and starts killing fleas within 12 hours. It’s waterproof after 24 hours and lasts up to 30 days. &nbsp;

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<h2>Find the right Advantage®&nbsp;II option for your pet and your lifestyle</h2>
Advantage®&nbsp;II comes in different dosage sizes and package quantities to match the unique needs of your pet and your lifestyle. Dosages are determined by your pet's weight so you get the right amount of protection for their size.
 
<a href="/us/our-products/advantage-ii/advantage-ii-cats">Advantage®&nbsp;II for Cats &gt;</a>
<a href="/us/our-products/advantage-ii/advantage-ii-dogs">Advantage®&nbsp;II for Dogs &gt;</a>

<h3>Fight the misery of biting fleas — protect your pet with Advantage®&nbsp;II today.</h3>

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<h2>Advantage®&nbsp;helps control fleas indoors and out</h2>
Fleas can infest your entire household: couches, carpets, you name it. Fight fleas from fur to fence™&nbsp;by treating your pet, home and yard with our full line of Advantage®&nbsp;products.&nbsp;
 
<a href="/us/collection/infestation">View all products and get coupon &gt;</a>

<h2>Advantage®&nbsp;II flea control for ferrets</h2>
Ferrets get fleas too. Advantage®&nbsp;II offers a once-a-month topical flea prevention and treatment for ferrets 10 weeks and older and weighing 1 pound or more.
 
<a href="/us/find-a-business">Find a retailer &gt;</a>

<h2>Advantage®&nbsp;II FAQs for cats and dogs</h2>

There is no expiration date required on the packaging by the EPA for Advantage® II for dogs. The product should be kept in its original packaging and stored as directed on the label.

Does Advantage® II for dogs expire?

Yes. Advantage® II is waterproof after 24 hours. However, we suggest bathing your dog before applying Advantage® II. Just make sure your dog is dry before application. If you choose to bathe your dog in between treatments, we recommend use of a general grooming shampoo for pets. Keep in mind that more frequent bathing may keep the product from working the full 30 days.

Can I bathe my dog after applying Advantage® II?

Yes! Your dog is free to take a dip after Advantage® II has been on for 24 hours. However, more frequent swimming may keep the product from working the full 30 days.

Can my dog go swimming after I apply Advantage® II?

No, do not use Advantage® II for dogs on cats. Please follow label directions for the application of our flea products.

Can I apply Advantage® II for dogs on my cats?

Advantage® II for dogs combines two active ingredients:
* Imidacloprid attacks the flea's nervous system - paralyzing and ultimately killing it.
* Pyriproxyfen is an insect growth regulator (IGR) that kills flea eggs and larvae.
This combination plays a crucial role in treating and preventing infestations, because:
* In an existing infestation, you might only be aware of the adult fleas, which only represent around 5% of the full infestation and are found on the pet.
* Immature flea life stages which live in the pet's environment consist of around 95% of the infestation and can be almost invisible to the naked eye.

How does Advantage® II for dogs work?

Advantage® II flea prevention is applied to your dog topically, spreading over the skin and hair. It kills fleas through contact, so fleas do not have to bite your dog to die. With oral flea medications, fleas have to bite your dog and ingest the medication before they are killed.

What is the difference between Advantage® II for dogs and oral flea products?

Use Advantage® II for dogs monthly, year-round to help keep your pet protected from fleas. Follow label directions for application.

How often can you use Advantage® II for dogs?

A single application of Advantage® II for dogs stops biting fleas for one month. However, if the dog has a severe infestation, retreatment within a month may be necessary. See product label for additional information.

How long does Advantage® II for dogs last?

Applying Advantage® II for dogs flea control to your canine companion is easy and convenient. Before applying, check the weight range and minimum age on the package to choose the appropriate product for your dog.
How to apply Advantage® II for dogs:
1. Remove the tube from packaging and open it by putting the cap on the other end and twisting to break the seal.
2. Place the tip of the tube on the skin between your dog's shoulder blades and gently squeeze to expel the solution on their skin. The number of application spots depends on the size and weight of your dog.
3. Lift the tube away from their skin, while maintaining pressure on the tube to make sure the product has all been squeezed out.
For more detailed instructions, watch our application video.&nbsp;

How do I apply Advantage® II for dogs?

You can use Advantage® II for dogs on puppies and dogs 7 weeks of age and older.&nbsp;

How old does my dog have to be to use Advantage® II for dogs?

Advantage® II for dogs kills fleas on dogs within 12 hours of application.&nbsp;

How long does Advantage® II for dogs take to work?

Do not have contact or allow children to have contact with the area treated with Advantage® II for dogs until completely dry.&nbsp;

Can I touch my dog after applying Advantage® II for dogs?

Do not contaminate water, food or feed by storage or disposal of Advantage® II.
* Storage: Store in cool dry place inaccessible to children and pets.
* Disposal and Container Handling: Non-refillable container. If empty: Do not reuse this container. Place in trash or offer for recycling if available. If partly filled: Call your local solid waste agency for disposal instructions. Never place unused product down any indoor or outdoor drain.

How do I dispose of Advantage® II?

Yes. Advantage® II is waterproof after 24 hours. However, we suggest bathing your cat before applying Advantage® II. Just make sure your cat is dry before application. If you choose to bathe your cat in between treatments, we recommend use of a general grooming shampoo for pets. Keep in mind that more frequent bathing may keep the product from working the full 30 days.

Can I bathe my cat after applying Advantage® II?

No, do not use Advantage® II for cats on dogs. Please follow label directions for the application of our flea products.

Can I use Advantage® II for cats on dogs?

No, you cannot split tubes of Advantage® II for cats between multiple cats. To successfully prevent and control fleas, cats must be treated with their own dose of Advantage® II. Follow label directions for application.

Can I split tubes of Advantage® II between my cats?

Advantage® II for cats combines two active ingredients:
* Imidacloprid attacks the flea's nervous system - paralyzing and ultimately killing it.
* Pyriproxyfen is an insect growth regulator (IGR) that kills flea eggs and larvae.
This combination plays a crucial role in treating and preventing infestations, because:
* In an existing infestation, you might only be aware of the adult fleas, which only represent around 5% of the full infestation and are found on the pet.
* Immature flea life stages which live in the pet's environment consist of around 95% of the infestation and can be almost invisible to the naked eye.

How does Advantage® II for cats work?

Advantage® II flea prevention is applied to your cat topically, spreading over the skin and hair. It kills fleas through contact, so fleas do not have to bite your cat to die. With oral flea medications, fleas have to bite your cat and ingest the medication before they are killed.

What is the difference between Advantage® II for cats and oral flea products?

Applying Advantage® II for cats flea control to your feline companion is easy and convenient. Before applying, check the weight range and minimum age on the package to choose the appropriate product for your cat.
How to apply Advantage® II for cats:
1. Remove the tube from packaging and open it by putting the cap on the other end and twisting to break the seal.
2. Part the hair where the cat's head and neck come together (base of the skull) and place the tip of the tube on the skin, gently squeezing to expel the entire solution out onto the skin.
3. Lift the tube away from their skin, while maintaining pressure on the tube to make sure the product has all been squeezed out.
For more detailed instructions, watch our application video.&nbsp;

How do I apply Advantage® II for cats?

You can use Advantage® II for cats on kittens and cats 8 weeks of age and older.&nbsp;

How old does my cat have to be to use Advantage® II?

There is no expiration date required on the packaging by the EPA for Advantage® II for cats. We recommend the product should be kept in its original packaging and stored as directed on the label.

Does Advantage® II for cats expire?

Advantage® II for cats kills fleas within 12 hours of application.

How long does Advantage® II for cats take to work?

Do not have contact or allow children to have contact with the area treated with Advantage® II for cats until completely dry.&nbsp;

Can I touch my cat after applying Advantage® II for cats?

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Advantage, Elanco and the diagonal bar logo are trademarks of Elanco or its affiliates.

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Advantage® II is a monthly flea treatment and flea control that kills fleas through contact. Find out how it works and answers to popular FAQs.

Advantage® II flea treatment for cats and dogs

Why choose Advantage® II flea control?

Advantage® II is fast and effective

Find the right Advantage® II option for your pet and your lifestyle

Fight the misery of biting fleas — protect your pet with Advantage® II today.

Advantage® helps control fleas indoors and out

Advantage® II flea control for ferrets

Advantage® II FAQs for cats and dogs

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