Profender® (emodepside/praziquantel) for Cats

Profender is a broad-spectrum deworming medication that effectively removes the most common intestinal worms infecting cats. Because it’s an easy to apply topical (spot-on), it removes the hassle and stress that comes along with giving a cat a pill. It is FDA-approved safe to effectively treat and control roundworms, hookworms and tapeworms.

Product Label 

CAUTION: Federal (U.S.A.) law restricts Profender® (emodepside/praziquantel) to use by or on the order of a licensed veterinarian.

HUMAN WARNINGS: Not for human use. Keep out of reach of children. Children should not contact application site for twenty-four (24) hours.

PRECAUTIONS: The effectiveness of this product when used before bathing has not been evaluated.

Profender® contains two active ingredients: emodepside and praziquantel. Emodepside is an ingredient found only in Profender® and is effective against adult and immature stages of roundworms and hookworms. Praziquantel, an ingredient used in several other effective deworming products, effectively removes tapeworms.  

Product Label 

CAUTION: Federal (U.S.A.) law restricts Profender® (emodepside/praziquantel) to use by or on the order of a licensed veterinarian.

HUMAN WARNINGS: Not for human use. Keep out of reach of children. Children should not contact application site for twenty-four (24) hours.

PRECAUTIONS: Use with caution in sick or debilitated cats.

Profender® comes in three different sizes based on your cat’s weight:

Profender® (emodepside/praziquantel) can be used on cats and kittens that are at least 8 weeks of age and weigh at least 2.2 lbs. Cats over 17.6 lbs. should be treated with the appropriate combination of tubes. In this situation, talk to your veterinarian for the appropriate combination of tubes.

Product Label 

CAUTION: Federal (U.S.A.) law restricts Profender® (emodepside/praziquantel) to use by or on the order of a licensed veterinarian.

HUMAN WARNINGS: Not for human use. Keep out of reach of children. Children should not contact application site for twenty-four (24) hours.

PRECAUTIONS: Use with caution in heartworm positive cats. The cats enrolled in the field study were antigen and antibody negative prior to entering the study. In a laboratory study, cats artificially infected with adult heartworms and treated with Profender® Topical Solution had fewer worms recovered than the placebo control group.

Profender® (emodepside/praziquantel) can be applied once every 30 days. One dose will kill and remove adult tapeworms and adult and immature stages of roundworms and hookworms. Due to your cat’s behavior and environment (going outdoors, hunting, exposure to fleas, etc.) reinfection is always a possibility in which case retreatment may be necessary. Talk to your veterinarian to find out the best course of action.

Product Label  

CAUTION: Federal (U.S.A.) law restricts Profender® (emodepside/praziquantel) to use by or on the order of a licensed veterinarian.

HUMAN WARNINGS: Not for human use. Keep out of reach of children. Children should not contact application site for twenty-four (24) hours.

PRECAUTIONS: Safe use of this product has not been evaluated in cats less than 8 weeks of age or weighing less than 2.2 lbs. (1 kg), in cats used for breeding, during pregnancy or in lactating queens.

Profender® (emodepside/praziquantel) is a prescription only product. Because of this, your cat will need an exam from a veterinarian and veterinarian-pet owner relationship needs to be established before it can be dispensed. Once a prescription is attained, Profender® can be purchased at veterinary clinics and online pharmacies.

Product Label 

CAUTION: Federal (U.S.A.) law restricts Profender® (emodepside/praziquantel) to use by or on the order of a licensed veterinarian.

HUMAN WARNINGS: Not for human use. Keep out of reach of children. Children should not contact application site for twenty-four (24) hours.

PRECAUTIONS: Use with caution in heartworm positive cats. The cats enrolled in the field study were antigen and antibody negative prior to entering the study. In a laboratory study, cats artificially infected with adult heartworms and treated with Profender® Topical Solution had fewer worms recovered than the placebo control group.

Applying Profender® for cats to your feline friend is simple and convenient. Before applying an Elanco topical product, check the weight range and minimum age on the package to choose the appropriate product for your cat.

Check the weight range and minimum age on the package to choose the appropriate product for your cat.

How to apply Profender® for cats:

For more detailed instructions, watch our application video.

CAUTION: Federal (U.S.A.) law restricts Profender® (emodepside/praziquantel) to use by or on the order of a licensed veterinarian.

HUMAN WARNINGS: Not for human use. Keep out of reach of children. Children should not contact application site for twenty-four (24) hours.

PRECAUTIONS: Use with caution in heartworm positive cats. The cats enrolled in the field study were antigen and antibody negative prior to entering the study. In a laboratory study, cats artificially infected with adult heartworms and treated with Profender® Topical Solution had fewer worms recovered than the placebo control group.

After a single dose of Profender® is applied, the worms are expelled through your cat’s feces. A second treatment should not be necessary. If re-infection occurs, the product can be applied again after 30 days.

CAUTION: Federal (U.S.A.) law restricts Profender® (emodepside/praziquantel) to use by or on the order of a licensed veterinarian.

HUMAN WARNINGS: Not for human use. Keep out of reach of children. Children should not contact application site for twenty-four (24) hours.

PRECAUTIONS: Use with caution in heartworm positive cats. The cats enrolled in the field study were antigen and antibody negative prior to entering the study. In a laboratory study, cats artificially infected with adult heartworms and treated with Profender® Topical Solution had fewer worms recovered than the placebo control group.

The active ingredients in Profender® are absorbed topically through your cat’s skin reaching the intestinal tract to kill and remove worms.

Always consult your veterinarian. The presence of parasites should be confirmed by fecal examination or based on clinical signs and history.

Product Label 

CAUTION: Federal (U.S.A.) law restricts Profender® (emodepside/praziquantel) to use by or on the order of a licensed veterinarian.

HUMAN WARNINGS: Not for human use. Keep out of reach of children. Children should not contact application site for twenty-four (24) hours.

PRECAUTIONS: Use with caution in heartworm positive cats. The cats enrolled in the field study were antigen and antibody negative prior to entering the study. In a laboratory study, cats artificially infected with adult heartworms and treated with Profender® Topical Solution had fewer worms recovered than the placebo control group.

Reinfection is always a possibility, in which case additional retreatment after 30 days may be necessary. Talk to your veterinarian to find the best course of action.

Product Label 

CAUTION: Federal (U.S.A.) law restricts Profender® (emodepside/praziquantel) to use by or on the order of a licensed veterinarian.

HUMAN WARNINGS: Not for human use. Keep out of reach of children. Children should not contact application site for twenty-four (24) hours.

PRECAUTIONS: Use with caution in heartworm positive cats. The cats enrolled in the field study were antigen and antibody negative prior to entering the study. In a laboratory study, cats artificially infected with adult heartworms and treated with Profender® Topical Solution had fewer worms recovered than the placebo control group.