Advantage® XD for cats: Flea protection without compromise

Made with our exclusive, naturally derived active ingredient, Advantage® XD for kittens and cats provides two months of flea protection in a single application and starts working in as little as 30 minutes.*

It's easy to buy Advantage® XD online. Just select your cat's weight, your preferred dosage and your favorite retailer below — no prescription required.

Next-generation flea prevention for cats

  • A calendar icon indicating two times more protection than other monthly flea treatment for cats
    Lasts 2x longer than monthly topicals†

    Advantage® XD kills fleas for two months in one dose, outlasting the typical six-week flea life cycle — and the monthly competition.

  • A time icon for fast-acting flea protection for cats and kittens
    Fast acting

    Advantage® XD starts killing fleas in as little as 30 minutes.* Some other topical treatments take as long as 24 hours to start working.

  • An icon of active ingredient in advantage xd flea treatment
    Sourced from nature

    Spinetoram, the Green Chemistry Challenge award1-winning ingredient in Advantage® XD, is derived from soil microbes that were found to be effective against fleas.

  • An icon of no flea pills or prescription for cats needed
    No pill or prescription required

    Unlike oral treatments, easy-to-apply Advantage® XD kills fleas through contact so they don’t have to bite your cat to die.

*Starts killing fleas in 30 minutes to 4 hours.
Based on label claims.

Flea protection for cats that acts fast* and outlasts the competition

Ready to get two months of flea protection in a single application with Advantage® XD (spinetoram) for cats?

Top questions about Advantage® XD for cats

Advantage® XD flea protection for small and large cat packs with a no-prescription icon and a two-month-treatment icon

Which size of Advantage® XD is right for my cat?

Advantage® XD is available in 1-packs (2 months of protection) and 2-packs (4 months of protection).

Small cat: 8 weeks and older and weighing between 1.8 and 9 pounds
Large cat: 8 weeks and older and weighing more than 9 pounds

Have more questions about Advantage® XD (spinetoram)?

Advantage, Elanco and the diagonal bar are trademarks of Elanco or its affiliates.

Always read, understand and follow the label and use directions.