Advantage® II for Dogs

Fight the misery of biting fleas with Advantage® II. A monthly topical flea prevention and treatment for dogs and puppies (at least 7 weeks old and 3 lbs. or more) that kills fleas through contact so they don’t have to bite your pet to die.

Why choose Advantage® II for Dogs?

  • green flea, flea egg, flea larvae icon
    Kills and prevents

    Kills and prevents fleas, flea eggs, flea larvae and chewing lice.

  • green icon of topical flea treatment applicator
    Easy to apply

    Easier than a flea collar. Goes on in seconds. Apply directly to dog’s skin — no hard-to-swallow pills.

  • green icon of 30 continuous days of protection from fleas
    30-day continuous protection

    Apply Advantage® II monthly. Starts killing fleas on your dog in 12 hours, waterproof after 24 hours.

  • green icon of no prescription required for Advantage II.
    No prescription needed

    Available over the counter whenever you need it.

black poodle playing with sprinkler in yard with green icons for fast and effective

Advantage® II for Dogs is fast and effective

Advantage® II flea treatment for dogs goes on in seconds, starts killing fleas within 12 hours and is waterproof after 24 hours. Simply reapply every 30 days.  

How does Advantage® II for Dogs work and for how long?

Advantage® II flea control for dogs is easy on you, easy on your dog and hard on parasites. This once-per month, odorless topical kills flea, flea larvae, flea eggs and chewing lice through contact so they don’t have to bite your dog to die. It continues to prevent re-infestation for 30 days.

Advantage II is available in 4 and 6 packs for multiple months of flea prevention and treatment for dogs

Find the right Advantage® II option for your dog and your lifestyle

Advantage® II comes in multiple package quantities and covers different dog sizes: puppies at least 7 weeks old and small dogs (3–10 lbs.), medium dogs (11–20 lbs.), large dogs (21–55 lbs.) and extra-large dogs (55+ lbs.) Enjoy the convenience of purchasing four or six months of Advantage® II flea protection per package. 

Fight the misery of biting fleas — protect your dog with Advantage® II today.

How to apply Advantage® II for Dogs


Hold the applicator tube in an upright position facing away from you and your pet’s face and eyes. Pull the cap off the tube.


Turn the cap around and place the other end of the cap back on the tube. Twist the cap to break the seal, and then remove the cap from the tube.


Your dog should be standing for easy application. Part the hair on your dog’s back, between the shoulder blades, until the skin is visible.


Place the tip of the tube on the skin and squeeze the tube to expel the entire contents directly on the skin, in one to four spots depending on your dog’s weight. See the Product Label for specific application instructions by weight.

Advantage House and Yard product collection for flea control

Getting rid of dog lice and fleas from fur to fence™

Fleas and lice can infest your entire household: couches, carpets, you name it. Fight them from fur to fenceTM by treating your dog, home and yard with our full line of Advantage® products.

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