K9 Advantix® II Flea, Tick and Mosquito Prevention for Dogs

Please consult your dog’s veterinarian for their recommendation.

A single application of K9 Advantix II keeps working for a month.

Yes! We suggest bathing your dog before applying K9 Advantix II. Your dog needs to be dry at the time of application. If you choose to bathe your dog in between treatments, we recommend use of a general grooming shampoo for pets.

A single application of K9 Advantix II remains effective for four weeks. However, if the dog has a severe infestation, retreatment within a month may be necessary. Do not retreat more than once every seven days, not to exceed 4 weekly treatments. After flea control is attained, return to a monthly treatment schedule. 

Although K9 Advantix II kills fleas on your dog, there may still be fleas in your dog’s environment that have since jumped on after treatment. Luckily, with K9 Advantix II, new fleas are killed within 2 hours with protection against further infestation for at least 4 weeks. As fleas die they are no longer able to stay hidden against your dog’s skin, and therefore you may also be seeing dying fleas coming to the surface of your dog’s fur coat.

K9 Advantix II kills existing fleas on dogs after initial application within 12 hours. New fleas that jump on the dog from the surroundings, such as grass, carpet and pet bedding, are then killed within 2 hours with protection against further flea infestation lasting at least 4 weeks.

Yes! Your dog is free to take a dip after K9 Advantix II has been on for 24 hours. More frequent swimming may keep the product from working for the full 30 days.

Not all products work the same way: K9 Advantix II is applied to the pet's skin, spreading the active ingredients over your dog's body to kill fleas and ticks through contact. No biting required!

Monitor your dog after application. In rare cases, some side effects may include signs of skin irritation such as redness, scratching or other signs of discomfort. Gastrointestinal signs such as vomiting or diarrhea have also been reported. If these or other side effects (such as lethargy or agitation) occur, consult your veterinarian or call Elanco Product & Veterinary Support at 888-545-5973.

Use only on dogs. DO NOT USE ON CATS or other animals. Do not apply to dogs weighing less than 4 lbs.

Remove applicator tube from the package. Use scissors and peel down foil.

Hold applicator tube in an upright position. Pull cap off tube.

Turn the cap around and place other end of cap back on tube.

Twist cap to break seal, then remove cap from tube.

The dog should be standing for easy application. Evenly apply the entire contents of the tube along the top of the dog's back, from the shoulder down to the base of the tail. The number of spots depends on the size and weight of your dog (please refer to the product label). At each spot, part the hair until the skin is visible. Place the tip of the tube on the skin and gently squeeze to expel a portion of the solution on the skin. Do not apply an excessive amount of solution at any one spot that could cause some of the solution to run off the side of the dog. Do not get this product in your dog’s eyes, or allow your dog to ingest this product.